三七总皂苷制剂临床应用
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主要参考文献

[1] 刘东平,杨军,丁丹.三七及其有效成分对血液系统的药理活性研究概况[J].中医药信息,2012,29(4):172-174.

[2] 陈江斌,孙小梅,方永有.三七总皂苷对冠心病心绞痛患者血浆内皮素-1和血小板功能的影响[J].中国中西医结合急救杂志,2009,16(2):96-98.

[3] 孙凤志,孙明江,吕旭潇.中药三七止血活血作用的研究进展[J].医学研究杂志,2013,42(9):24-26.

[4] 张志军,江文,万群.人参皂甙Rg1扩张兔基底动脉作用及其机制[J].心脏杂志,2003,15(4):313-315.

[5] 古丽丽,王慧敏.三七总皂苷对血液及造血系统的药理作用研究进展[J].首都医药,2012,9(10):37-38.

[6] 苏雅,赵益桂,张宗鹏,等.三七三醇皂甙对动物血小板功能及血栓形成的影响[J].中草药,1996,27(11):666-669.

[7] 甘雨,徐惠波,孙晓波.三七总皂苷的药理作用研究进展[J].时珍国医国药,2007,18(5):1251-1252.

[8] 詹合琴,李平法,杨锦南,等.三七皂苷Rg1对t-PA和PAI-1水平的影响[J].中国药理学通报,2006,22(7):869-872.

[9] 吴光华,黄岩杰,李晓丽,等.三七活血与止血机制及其改善肾脏病血瘀证的作用特点[J].中华中医药杂志,2019,34(7):3140-3142.

[10] 王珍,杨靖亚,宋书杰,等.三七素对凝血功能的影响及止血机制[J].中国新药杂志,2014,23(3):356-359.

[11] HUANG Lingfang,SHI Hailian,GAO Bo,et al.Decichine enhances hemostasis of activated platelets via AMPA receptors[J].Thrombosis Research,2014,133(5):848-854.

[12] DING Shilan,WANG Min,FANG Song,et al.D-dencichine regulates thrombopoiesis by promoting megakaryocyte adhesion,migration and proplatelet formation[J/OL].Frontiers in Pharmacology,2018,9:1-16[2020-04-03].https://doi.org/10.3389/fphar.2018.00297.DOI:10.3389/fphar.2018.00297.

[13] 冯冰虹,徐位良,李娟好,等.复方三七浸膏对增强苯肾上腺素收缩大鼠的主动脉环和降低兔的血小板黏附性的作用机理[J].广东药学,2005,15(4):59-62.

[14] 杨志刚,郑剑伟,忻晨.中药三七对血液系统和心脑血管系统的影响[J].中国兽药杂志,2008,42(3):46-50.

[15] 郑茵红,高瑞兰,朱大元,等.三七总皂苷及其单体对入骨髓造血祖细胞增殖作用的研究[J].中国中西医结合急救杂志,2003,10(3):135-137.

[16] 高瑞兰,徐卫红,林筱洁,等.三七皂苷对造血细胞GATA-1和GATA-2转录调控蛋白的诱导作用[J].中华血液学杂志,2004,25(5):281-284.

[17] LIU Y,XIE M X,KANG J,et al.Studies on the interaction of total saponins of panax notoginseng and human serum albumin by fourier transform infrared spectroscopy[J].Sectrochimica Acta Part A,2003,59(12):2747-2758.

[18] NG T B,LIU F,WANG H X.The antioxidant effects of aqueous and organic extracts of Panax quinquefolium,Panax notoginseng,Codonopsis pilosula,Pseudostellaria heterophylla and Glehnia littoralis[J].Ethnopharmacol,2004,93(2-3):285-288.

[19] LIU Jingjing,WANG Yitao,QIU Lan,et al.Saponins of Panax notoginseng:chemistry,cellular targets and therapeutic opportunities in cardiovascular diseases[J].Expert Opin Investig Drugs,2014,23(4):523-539.

[20] 樊清波,李小威,简立国,等.三七总皂苷对大鼠心肌梗死后血管新生及微小 RNA-21 表达的影响[J].郑州大学学报(医学版),2014,49(1):48-52.

[21] 苏明,温进坤,郑斌,等.三七总皂苷对血管平滑肌细胞迁移的抑制作用及机制探讨[J].中国药理学通报,2010,26(10):1326-1329.

[22] 王欣,刘志辉,杨同,等.三七总皂苷对缺血再灌注大鼠神经功能及海马区葡萄糖转运蛋白-1表达的影响[J].中华脑科疾病与康复杂志(电子版),2015,5(3):168-172.

[23] 徐士欣,马惠宁,王成益,等.三七总皂苷对脑缺血再灌注损伤大鼠缺氧诱导因子1和基质金属蛋白酶表达的影响[J].中华老年心脑血管病杂志,2016,18(8):859-862.

[24] 贺旭,葛金文,黄俊.总皂苷对全脑缺血成年大鼠侧脑室室管膜区神经再生的影响[J].中草药,2016,47(9):1535-1540.

[25] 马立,吴明华,梁森,等.三七总皂苷对脑缺血后神经血管的保护机制[J].吉林中医药,2013,33(7):720-723.

[26] 骆志坚,熊念,王涛,等.三七总皂苷对高血压性脑出血患者血肿吸收及神经功能恢复的影响[J].卒中与神经疾病,2015,22(4):234-237.

[27] 吴江立,安胜军,安然,等.三七总皂苷对高脂血症金黄地鼠降脂作用的研究[J].河北中医药学报,2019,34(3):5-15.

[28] 邝颖颐,黄经光,彭荣,等.三七总皂苷对血脂异常患者内皮祖细胞数量的影响[J].亚太传统医药,2014,10(16):90-91.

[29] 江小萍,曾凡鹏,刘首明,等.三七总皂苷对动脉粥样硬化患者血管炎症因子及颈动脉内膜中层厚度和斑块的影响[J].中国中医急症,2015,24(10):1753-1779.

[30] 王莹,禇扬,李伟,等.三七中皂苷成分及其药理作用的研究进展[J].中草药,2015,46(9):1381-1392.

[31] 李响,马雪涛,吴振起,等.三七总皂苷对白细胞黏附效应与黏附分子表达调控的研究[J].中国中药杂志,2009,34(13):1734-1736.

[32] WANG Nan,WAN Jianbo,CHAN Shunwan,et al.Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion[J].Chin Med,2011,6(37):1-12.

[33] 刘桂林,窦迎春,乔云.三七总皂苷对动脉粥样硬化血管内皮的保护作用[J].中西医结合心脑血管病杂志,2013,11(9):1094-1096.

[34] LI Z,LI H,ZHAO C,et al.Protective effect of Notoginsenoside R1 on an APP/PS1 mouse model of Alzheimer's disease by up-regulating insulin degrading enzyme and inhibiting Aβ accumulation[J].CNS Neurol Disord Drug Targets,2015,14(3):360-369.

[35] MA B,MENG X,WANG J,et al.Notoginsenoside R1 attenuates amyloid-βinduced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation[J].Int Immunopharmacol,2014,22(1):151-159.

[36] MENG X,LUO Y,LIANG T,et al.Gypenoside XVII enhances lysosome biogenesis and autophagy flux and accelerates autophagic clearance of amyloid-β through TFEB activation[J].J Alzheimers Dis,2016,52(3):1135-1150.

[37] ZHAO H H,DI J,LIU W S,et al.Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation[J/OL].Behav Brain Res,2013,241:228-234[2020-03-15].http://dx.doi.org/10.1016/j.bbr.2012.11.037.

[38] DU Y,FU M,WANG Y T,et al.Neuroprotective effects of Ginsenoside Rf on amyloid-β-induced neurotoxicity in vitro and in vivo[J].J Alzheimers Dis,2018,64(1):309-322.

[39] SHI C,ZHENG D D,FANG L,et al.Ginsenoside Rg1 promotes nonamyloidgenic cleavage of APP via estrogen receptor signaling to MAPK/ERK and PI3K/Akt[J].Biochim Biophys Acta,2012,1820(4):453-460.

[40] MENG X,WANG M,SUN G,et al.Attenuation of Aβ25-35-induced parallel autophagic and apoptotic cell death by gypenoside XVII through the estrogen receptor-dependent activation of Nrf2/ARE pathways[J].Toxicol Appl Pharmacol,2014,279(1):63-75.

[41] 聂娟,唐标.基于系统药理学分析三七总皂苷干预脑血管疾病的作用机制[J].湖南中医药大学学报,2018,38(9):1032-1037.

[42] XIE W,ZHOU P,SUN Y,et al.Protective Effects and Target Network Analysis of Ginsenoside Rg1 in Cerebral Ischemia and Reperfusion Injury:A Comprehensive Overview of Experimental Studies[J].Cells,2018,7(12):1-18.

[43] 汪梦霞,赵静宇,孙冬梅,等.三七总皂苷对6-羟基多巴胺诱导SH-SY5Y细胞损伤的保护作用及可能机制[J].药学学报,2016,51(6):898-906.

[44] 赵静宇,汪梦霞,赵自明,等.基于Nrf2信号通路的三七总皂苷对Aβ25-35诱导PC12细胞凋亡的保护作用机制研究[J].中国药理学通报,2016,32(3):343-349.

[45] 马丽炎,肖培根.三七皂甙对突触体谷氨酸受体特异性结合的影响[J].中国药理学通报,1998,14(4):309.

[46] 张仁丽.三七总皂苷在昆明小鼠急性炎性内脏痛中的作用及机制研究[D].衡阳:南华大学,2016.

[47] 姚青,马晓东,张茜,等.三七总皂苷对糖尿病早期大鼠视网膜功能的保护作用[J].宁夏医学杂志,2014,36(3):204-206.

[48] 杨惠,罗丹,高明,等.三七总皂苷抑制星形胶质细胞活化改善脂多糖导致的小鼠抑郁样行为[J].解剖学杂志,2019,42(1):26-30.

[49] XIANG H,LIU Y X,ZHANG B B,et al.The antidepressant effects and mechanism of action of total saponins from the caudexes and leaves of Panax notoginseng in animal models of depression[J/OL].Phytomedicine,2011,18:731-738[2019-06-15].https://doi.org/10.1016/j.phymed.2010.11.014.DOI:10.1016/j.phymed.2010.11.014.

[50] MACISAAC R J,EKINCI E I,JERUMS G.Markers of and risk factors for development and progression of diabetic kidney disease[J].Am J Kidney Dis,2014,63(2)(suppl 2):S39-S62.

[51] 周静鑫,郭璇,吴欣莉,等.三七总皂苷对糖尿病肾病小鼠足细胞保护作用的机制研究[J].中华中医药杂志,2014,29(5):1316-1321.

[52] 程苏,屠庆年,陆付耳,等.三七总苷对糖尿病大鼠早期肾脏高滤过及血管内皮功能的影响[J].医药导报,2005,24(6):467-470.

[53] 严素娟.血塞通注射液治疗糖尿病肾病的疗效观察[J].湖北中医杂志,2013,35(4):47-48.

[54] 林琳,朱伟平,郑晶,等.三七总皂苷对高糖诱导的肾小管上皮细胞转分化的研究[J].时珍国医国药,2013,24(8):2053-2054.

[55] 孙英豪,高剑,高金平.三七总皂苷对庆大霉素所致大鼠肾毒性的保护作用[J].现代中西医结合杂志,2011,20(25):3141-3142.

[56] 杨志刚.中药三七对神经系统和免疫系统的影响[J].中国药房,2008,19(18):1424-1426.

[57] CICERO A F G,VITALE G,SAVION G,et al.Panax notoginseng(Burk.)effects on fibrinogen and lipid plasma level in rats fed on a high-fat diet[J].Phytother Res,2003,17(2):174-178.

[58] 屈泽强,谢智光,王乃平,等.三七总皂苷抗衰老作用的实验研究[J].广州中医药大学学报,2005,22(2):130-132.

[59] 张嘉麟,徐文安,杨荫康,等.三七中人参皂甙对老年鼠血浆脂质及其代谢产物含量的影响[J].昆明医学院学报,2001,22(1):45-46.

[60] 钟琳.三七三醇皂苷对胆红素中毒性脑病的干预研究[J].中国妇幼保健,2012,27(16):2477-2478.

[61] 张荣华,李景怡,陈如泉,等.三七总皂苷对肝纤维化大鼠肝脏超微结构的影响[J].第三军医大学学报,2005,27(24):2410-2413.

[62] 马加庆,云宇,后文俊,等.三七总皂苷对药物性肝损伤小鼠的保护作用[J].中国实验方剂学杂志,2013,19(23):246-249.

[63] 孙晓芳,杨长福,黄春芳,等.三七总皂苷对肺纤维化小鼠肺组织胶原影响的实验研究[J].中医药学报,2010,38(5):14-16.

[64] 宋永祥,张纪银,徐刚,等.三七总皂甙对兔肺挫伤治疗作用的实验研究[J].贵州医药,2011,35(8):683-686.

[65] 郑茵红,高瑞兰,朱大元,等.三七总皂苷及其单体对人骨髓造血祖细胞增殖作用的研究[J].中国中西医结合急救杂志,2003,10(3):135-137.

[66] 高瑞兰,徐卫红,林筱洁,等.三七皂甙对造血细胞GATA-1和GATA-2转录调控蛋白的诱导作用[J].中华血液学杂志,2004,25(5):281-284.

[67] 尚西亮,傅华群,刘佳,等.三七总皂甙对人肝癌细胞的抑制作用[J].中国临床康复,2006,10(23):121-123.