VMware NSX Cookbook
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Enabling NSX in a brownfield environment

When enabling a vSphere cluster for NSX in a brownfield environment, it is important to be cognizant that any preconfigured DFW firewall rules have the potential to impact virtual machines on the newly-configured vSphere cluster. Therefore, it is extremely important to ensure that the default Distributed Firewall rule remains as allow any any. Changing to deny before defining rules for allowing legitimate traffic from/to virtual machines will cause traffic blackholing. 

As a best practice, vCenter server and virtual machines that require promiscuous mode should be excluded from the DFW if you are not planning to protect them. To learn how to exclude virtual machines from the DFW, refer to Chapter 6Configuring VMware NSX Distributed Firewall (DFW) and SpoofGuard.