7 Treatment
7.1 Determine the treatment place according to the severity of the disease. The “Suspected cases and confirmed cases” is deleted and “Cases should be isolated and treated in designated hospitals with effective isolation and protective conditions. Confirmed cases can be admitted to the same ward.” is added.
7.2 Antiviral treatment. The description of “no effective antiviral treatment is currently confirmed” is deleted. “Chloroquine phosphate(500 mg for adult,twice per day)” and “Arbidol(200 mg for adult, three times per day)” are added as trial drugs. Combinations of ribavirin and interferon or lopinavir/ritonavir are recommended. The course of treatment with trial drugs should be ≤10 days. Effects of trial drugs are recommended to be evaluated during clinical usage. Simultaneously use of three or more types of antiviral drugs is not recommended and relative drug treatment should stop if unbearable side effects occur.
7.3 As for treatment to severe and critical cases, “convalescent plasma therapy” is added and recommended for treating rapidly developed cases,severe cases and critical cases. Administrations and dosage refer to Clinical Plasma Therapy Plan for Corona Virus Disease 2019 Convalescents during Recovery(Tentative First Edition).
7.4 Other treatments. “Extracorporeal blood purification technology should be considered if possible” is changed to “Plasma change, adsorption, perfusion, blood/plasma filtering and other extracorporeal blood purification technologies should be considered if possible” for critical cases with severe inflammatory reactions.
7.5 Chinese medicine treatment. The Diagnosis and Treatment Plan of Corona Virus Disease 2019 (Tentative Fifth Revised Edition)is modified and complemented based on the in-depth observation and treatment of cases, summary and analysis of national-wide prescriptions of traditional Chinese medicine, screening effective experiences and prescriptions, and announcement of the Recommendation of Lung-Clearing and Detoxification Soup in the Treatment of Corona Virus Disease 2019 by Integrated Traditional Chinese and Western Medicine, the Diagnosis and Treatment Plan of Severe and Critical Corona Virus Disease 2019 Cases (Tentative Second Edition), and the Management Regulation of Mild and General Corona Virus Disease 2019 Cases.The classifications of stages of disease are consistent with the fifth revised edition and the traditional Chinese medicine treatment is divided into medical observation period and clinical treatment period(for confirmed cases), which is further divided into mild, general, severe, critical and recovery periods. Chinese patent medicine is recommended for medical observation period therapy while commonly used prescription, lungclearing and detoxification soup is recommended for clinical treatment period. Interpretations of clinical manifestations, recommended prescription and dosage and intake methods are provided separately for mild, general,severe, critical and recovery periods. The specific usages of Chinese patent medicine(including traditional Chinese medicine injection)for severe and critical cases are added in the meantime. Different regions can refer to the recommended prescriptions for dialectical treatment according to the disease conditions, local climate characteristics, and different physical conditions.